The Basics Of Our Business
Almost all drugs target proteins
60% of approved drugs target membrane proteins
Most of these drugs have limited selectivity, meaning they act on more than one protein and may cause undesirable effects
Many of these drugs have been around for years, and it’s hard to develop better ones
There is a high need for new, effective, and safer drugs to treat diseases like cancer, diabetes, inflammation and neurology
To facilitate the discovery of new drugs, scientists need to be able to work with stable membrane proteins
Purifying membrane proteins can be very challenging, mostly because they are hydrophobic (water-hating) and/or extremely flexible
We use cells to determine which protein building blocks to change to make working with membrane proteins easier
We license this technology to other companies, and also use it to discover our own drug candidates